SCHEMBL22188151

SCHEMBL22188151

O=[N+]([O-])c1ccccc1Nc1c(Br)cccc1Br

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.64
ALDH1A1 P00352 4/20 0.64
TDP1 Q9NUW8 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
CASP7 P55210 1/20 0.64
MEN1 O00255 6/20 0.57
KMT2A Q03164 6/20 0.57
MAPT P10636 4/20 0.57
GAA P10253 2/20 0.57
PKM P14618 1/20 0.57
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
EPAS1 Q99814 1/20 0.49
KDM4E B2RXH2 1/20 0.48
ASPH Q12797 1/20 0.48
KDM8 Q8N371 1/20 0.48
HSP90AA1 P07900 1/20 0.48
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
CXCR2 P25025 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30677987 1.00 MAPK1 (0.64) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL31072242 0.88 CXCR2 (0.50) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL22964930 0.88 CXCR2 (0.50) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL28137679 0.86 MAPK1 (0.62) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL18022833 0.85 MAPK1 (0.58) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL27083668 0.84 EPAS1 (0.62) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL11901308 0.81 MEN1 (0.66) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL397773 0.81 MAPK1 (0.77) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL26468007 0.81 TDP1 (0.77) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL27083675 0.81 MAPK1 (0.53) MAPK1ALDH1A1TDP1L3MBTL1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577268-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-03-17 US disclosed
US-20260022294-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-22 US disclosed
US-20240298520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-09-05 US disclosed
US-20240122059-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-04-11 US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 US disclosed
US-11814403-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-20230159578-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230065887-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-03-02 US disclosed
EP-4134371-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-02-15 EP disclosed
EP-3715353-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-09-14 EP disclosed
US-20210284672-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-16 US disclosed
US-20210249602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-12 US disclosed
EP-3715353-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-09-30 EP disclosed
US-20200216481-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230065887-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, DRD3 MAPK1 2092/4885ALDH1A1 710/4885TDP1 2263/4885
US-20210284672-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDCD1, TEC, PDCD4 MAPK1 1587/4885ALDH1A1 870/4885TDP1 1607/4885
US-20210249602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OTC, OSBP, OCIAD2 MAPK1 4056/4885ALDH1A1 519/4885TDP1 2612/4885
US-11814403-B2 Organic electroluminescent materials and devices PDCD1, TEC, PDCD4 MAPK1 1583/4885ALDH1A1 863/4885TDP1 1619/4885
US-12577268-B2 Organic electroluminescent materials and devices LBR, RPS4X, RPS6 MAPK1 2495/4885ALDH1A1 1496/4885TDP1 3962/4885
US-20260022294-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE GRIN2C, GRIA1, SCO2 MAPK1 899/4885ALDH1A1 643/4885TDP1 4508/4885
US-20200216481-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDCD1, TEC, PDCD4 MAPK1 1583/4885ALDH1A1 863/4885TDP1 1619/4885
US-20230159578-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, DRD3 MAPK1 2092/4885ALDH1A1 710/4885TDP1 2263/4885
US-20240122059-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, DRD3 MAPK1 2092/4885ALDH1A1 710/4885TDP1 2263/4885
US-11917900-B2 Organic electroluminescent materials and devices OTC, OSBP, OCIAD2 MAPK1 4056/4885ALDH1A1 519/4885TDP1 2612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.