Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486190 | 0.91 | POLB (0.47) | ALDH1A1PAX8LMNARAB9ACDK2 | |
| SCHEMBL22188914 | 0.90 | POLB (0.62) | ALDH1A1LMNARAB9ACDK2POLB | |
| SCHEMBL9485938 | 0.88 | MAPK1 (0.60) | ALDH1A1PAX8LMNAPOLBMAPT | |
| SCHEMBL5327849 | 0.82 | CDK2 (0.56) | ALDH1A1CDK2POLBMAPTTDP1 | |
| SCHEMBL6488744 | 0.82 | MAPT (0.49) | LMNACDK2POLBMAPT | |
| SCHEMBL27709706 | 0.82 | CDK2 (0.46) | ALDH1A1LMNACDK2POLBMAPT | |
| SCHEMBL22188915 | 0.80 | MAPT (0.48) | LMNACDK2POLBMAPTMEN1 | |
| SCHEMBL29263665 | 0.79 | NR4A2 (0.59) | ALDH1A1LMNACDK2POLBMAPT | |
| SCHEMBL7508094 | 0.79 | CDK2 (0.46) | LMNACDK2POLBMAPTMEN1 | |
| SCHEMBL22188909 | 0.79 | PLA2G4A (0.52) | ALDH1A1CDK2POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752585-B2 | Process for the preparation of Zafirlukast and analogs thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-08-25 | — | — | US | disclosed |
| US-20200216390-A1 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST AND ANALOGS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752585-B2 | Process for the preparation of Zafirlukast and analogs thereof | CHUK, HRH2, CTSH | ALDH1A1 2301/4885PAX8 4724/4885LMNA 1616/4885 |
| US-20200216390-A1 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST AND ANALOGS THEREOF | CHUK, CTSH, HRH2 | ALDH1A1 2602/4885PAX8 4797/4885LMNA 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.