Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pempidine SCHEMBL28572819 | 0.83 | TSHR (0.53) | GPR84PPARGPPARDPPARATSHR | |
| Stearic Acid SCHEMBL9813639 | 0.81 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4453278 | 0.79 | TSHR (0.43) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanedioate SCHEMBL30741313 | 0.79 | TSHR (0.46) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL480504 | 0.79 | TSHR (0.46) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL25268586 | 0.78 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28964404 | 0.78 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1148214 | 0.78 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL28454439 | 0.78 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL392645 | 0.78 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111434706-A | Block copolymer antistatic agent, antistatic polyolefin film comprising same, and preparation method thereof | AICELLO 美林化学株式会社 | 2020-07-21 | — | — | CN | disclosed |
| US-20200216646-A1 | BLOCK COPOLYMERIC ANTISTATIC AGENT COMPRISING HYDROPHILIC BLOCKS AND HYDROPHOBIC BLOCKS, ANTISTATIC POLYOLEFIN FILM COMPRISING THE SAME AND PREPARATION METHOD THEREOF | AICELLO MILIM CHEMICAL CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
| CN-110678448-A | Triazine compound, curable composition, method for producing cured product, and cured product thereof | 株式会社ADEKA | 2020-01-10 | — | — | CN | disclosed |
| CN-102844365-B | Granulated resin additive composition | ADEKA CORP | 2014-12-03 | — | — | CN | disclosed |
| CN-101952344-B | Aqueous polyurethane resin composition and article coated with the same | ADEKA CORP | 2013-04-17 | — | — | CN | disclosed |
| CN-1922260-B | Flame retardant composition with enhanced fluidity, flame retardant resin composition and molding thereof | ADEKA CORP | 2011-05-25 | — | — | CN | disclosed |
| CN-1914242-B | Aqueous dispersion type polyurethane composition | ADEKA CORP | 2011-05-18 | — | — | CN | disclosed |
| CN-101952344-A | Aqueous polyurethane resin composition and article coated with the same | ADEKA CORP | 2011-01-19 | — | — | CN | disclosed |
| CN-101563418-A | Vinyl chloride resin composition | ADEKA CORP (JP) | 2009-10-21 | — | — | CN | disclosed |
| CN-1922260-A | Flame retardant composition with enhanced fluidity, flame retardant resin composition and molding thereof | ASAHI DENKA CO LTD (JP) | 2007-02-28 | — | — | CN | disclosed |
| CN-1914242-A | Aqueous dispersion type polyurethane composition | ASAHI DENKA CO LTD (JP) | 2007-02-14 | — | — | CN | disclosed |