Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CCNH | P51946 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192510 | 0.76 | CTSA (0.39) | MAPK14CDK2SLC2A1CTSAALDH1A1 | |
| SCHEMBL2192291 | 0.76 | SLC2A1 (0.48) | MAPK14CDK2SLC2A1CTSAALDH1A1 | |
| SCHEMBL2188610 | 0.75 | MAPK14 (0.39) | MAPK14CDK2SLC2A1CTSAALDH1A1 | |
| SCHEMBL2217811 | 0.72 | CTSA (0.39) | MAPK14CDK2SLC2A1CTSAHSD17B10 | |
| SCHEMBL14247763 | 0.68 | SLC6A2 (0.53) | ALDH1A1KDM4ETSHRLMNACYP1A2 | |
| SCHEMBL3637962 | 0.68 | CYP2C19 (0.48) | ALDH1A1DPP4CYP2C19 | |
| SCHEMBL14032681 | 0.68 | ALDH1A1 (0.40) | MAPK14CDK2CCNT1CDK1CCNB1 | |
| SCHEMBL10441591 | 0.65 | ALDH1A1 (0.39) | MAPK14CDK2CDK1CCNB1CTSA | |
| SCHEMBL30230728 | 0.62 | ALDH1A1 (0.36) | MAPK14CDK2CDK1CCNB1SLC2A1 | |
| SCHEMBL21988476 | 0.62 | NPC1 (0.46) | ALDH1A1HSD17B10KDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | ARQULE, INC. (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | MKI67, CDK4, ABL1 | MAPK14 3207/4885CDK2 12/4885CCNT1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.