SCHEMBL2219282

SCHEMBL2219282

FC(F)(F)C(F)(Br)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3893396 0.89 LMNA (0.38) LMNA
SCHEMBL25358607 0.80 LMNA (0.33) LMNA
SCHEMBL1039199 0.80 LMNA (0.41) LMNA
SCHEMBL8086730 0.77 LMNA (0.39) LMNA
SCHEMBL6622516 0.77 LMNA (0.47) LMNA
SCHEMBL565110 0.74 LMNA (0.30) LMNA
SCHEMBL565111 0.74 LMNA (0.30) LMNA
SCHEMBL22390139 0.74 LMNA (0.30) LMNA
SCHEMBL18748275 0.74 LMNA (0.30) LMNA
SCHEMBL7743500 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025044027-A1 PREPARATION METHOD FOR HIGH-CONTENT 2-TRIFLUOROMETHYL-4-HEPTAFLUOROISOPROPYL ANILINE 浙江宇龙药业有限公司 2025-03-06 WO claimed
CN-114394903-B Synthesis method of perfluoroalkyl substituted aniline 江苏联化科技有限公司 2024-11-08 CN claimed
CN-117986079-A Method for continuously preparing 2-bromoheptafluoropropane in full flow path through high-flux micro-channels 山东丰源生物医药科技有限公司 2024-05-07 CN claimed
CN-115073300-B 4- (perfluoropropane-2-yl) -2-trifluoromethyl aniline and preparation method and application thereof 江西天宇化工有限公司 2024-04-05 CN claimed
CN-117623938-A Preparation method of high-content 2-trifluoromethyl-4-heptafluoroisopropylaniline 浙江宇龙药业有限公司 2024-03-01 CN claimed
CN-117164428-B Preparation method of hydrofluoroolefin 北京宇极科技发展有限公司 2024-02-09 CN claimed
CN-117164428-A Preparation method of hydrofluoroolefin 北京宇极科技发展有限公司 2023-12-05 CN claimed
CN-116754533-A Long afterglow homogeneous detection method 复旦大学 2023-09-15 CN claimed
CN-114105821-B Preparation method of heptafluoroisobutyronitrile 浙江省化工研究院有限公司 2023-09-12 CN claimed
CN-116693419-A Preparation method of heptafluoroisobutyronitrile 浙江省化工研究院有限公司 2023-09-05 CN claimed
CN-103044189-A Preparation device and method of 2-bromo heptafluoropropane JUHUA GROUP TECHNOLOGY CT 2013-04-17 CN claimed
CN-101768047-A Method for preparing 2-bromo-1,1,1,2,3,3,3-heptafluoropropane ZHEJIANG LANTIAN ENVIRONMENTAL 2010-07-07 CN claimed
EP-1418169-B1 Process for the preparation of polyhalogenoalkylaryl compounds SALTIGO GMBH (DE) 2009-02-25 EP claimed
CN-1498882-A Prepn. of polyhalid alkane 2004-05-26 CN claimed
US-20040092762-A1 Polyhaloalkylaryls LANXESS DEUTSCHLAND GMBH (DE) 2004-05-13 US claimed
US-20040092781-A1 Preparation of polyhaloalkanes BAYER AKTIENGESELLSCHAFT (DE) 2004-05-13 US claimed
EP-1418163-A1 Process for the preparation of polyhaloalkanes Bayer Chemicals AG (DE) 2004-05-12 EP claimed
EP-1418169-A2 Polyhalogenoalkylaryl compounds Bayer Chemicals AG (DE) 2004-05-12 EP claimed
US-5093166-A Bonded, crosslinked layers of hexafluoropropylene-tetrafluoroethylene-vinylidene fluoride terpolymer and acrylonitrile-butadiene copolymer; hoses TOKAI RUBBER INDUSTRIES, LTD. (JP) 1992-03-03 US claimed
US-4887647-A CROSSLINKED FLUOROPOLYMER TOKAI RUBBER INDUSTRIES, LTD. (JP) 1989-12-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092762-A1 Polyhaloalkylaryls LIPA, PCBP1, ABHD16A LMNA 490/4885
US-20040092781-A1 Preparation of polyhaloalkanes PCBP1, CYP4F8, CYP4F3 LMNA 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.