Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | PGK1 | P00558 | 1/20 | 0.59 |
| ▸ | PGK2 | P07205 | 1/20 | 0.59 |
| ▸ | MGMT | P16455 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21145007 | 0.93 | SLC29A1 (0.74) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| SCHEMBL20633954 | 0.92 | SLC29A1 (0.59) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| SCHEMBL20633996 | 0.91 | SLC29A1 (0.51) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| SCHEMBL2218888 | 0.85 | ADORA2A (0.70) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| SCHEMBL8971138 | 0.85 | SLC29A1 (0.62) | SLC29A1ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL8971129 | 0.85 | SLC29A1 (0.62) | SLC29A1ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL30464934 | 0.85 | CYP2C19 (0.66) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| Nelarabine SCHEMBL20769831 | 0.84 | CYP2C19 (0.71) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| Nelarabine SCHEMBL14031852 | 0.84 | CYP2C19 (0.71) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 | |
| Nelarabine SCHEMBL2143756 | 0.84 | CYP2C19 (0.71) | SLC29A1ADORA2AADORA2BCYP2C19ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141460-A2 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141459-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |