SCHEMBL22193977

SCHEMBL22193977

CNC(=O)[C@H](Cc1ccc(OS(=O)(=Nc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)N2CCCC2)cc1)NC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 2/20 0.38
▸ SLC5A1 P13866 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ BCL2 P10415 1/20 0.37
▸ HDAC8 Q9BY41 1/20 0.37
▸ P2RX7 Q99572 3/20 0.35
▸ PTPN1 P18031 2/20 0.35
▸ CTSS P25774 3/20 0.35
▸ CTSK P43235 2/20 0.35
▸ P4HB P07237 1/20 0.35
▸ CTSL P07711 1/20 0.34
▸ CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22193917 0.94 PTPN1 (0.39) SLC5A2SLC5A1L3MBTL1BCL2P2RX7
SCHEMBL24120444 0.92 P2RX7 (0.42) SLC5A2SLC5A1L3MBTL1P2RX7
SCHEMBL22193918 0.92 P2RX7 (0.42) SLC5A2SLC5A1L3MBTL1P2RX7
SCHEMBL22193991 0.89 PTPN1 (0.38) SLC5A2SLC5A1BCL2P2RX7PTPN1
SCHEMBL24120443 0.85 KLK5 (0.34) SLC5A2SLC5A1L3MBTL1BCL2P2RX7
SCHEMBL24120462 0.80 SLC5A2 (0.43) SLC5A2SLC5A1BCL2
SCHEMBL24120438 0.80 PTPN1 (0.40) SLC5A2SLC5A1BCL2HDAC8PTPN1
SCHEMBL22193920 0.80 PTPN1 (0.40) SLC5A2SLC5A1BCL2HDAC8PTPN1
SCHEMBL24120439 0.79 SLC5A2 (0.40) SLC5A2SLC5A1BCL2P2RX7
SCHEMBL22193922 0.79 SLC5A2 (0.40) SLC5A2SLC5A1BCL2P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210393795-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KR) 2021-12-23 — — US disclosed
WO-2020141460-A2 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KR) 2020-07-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393795-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF ANTXR2, VIP, TNFRSF9 SLC5A2 4872/4885SLC5A1 4882/4885L3MBTL1 3538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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