SCHEMBL22197306

SCHEMBL22197306

CNCCCOC1=CCCC=C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 3/20 0.42
HRH1 P35367 2/20 0.36
SLC6A4 P31645 2/20 0.36
HTR1D P28221 1/20 0.35
KDM4E B2RXH2 5/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
ALDH1A1 P00352 4/20 0.32
CHRM1 P11229 1/20 0.32
L3MBTL4 Q8NA19 1/20 0.31
L3MBTL3 Q96JM7 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
NSD2 O96028 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4390758 0.79 LTA4H (0.33) ALDH1A1CHRM1CYP1A2CYP3A4CYP2C9
SCHEMBL8046976 0.77 CYP1A2 (0.32) CYP1A2
SCHEMBL13068826 0.76 TSHR (0.43) HTR1BHTR1DKDM4EPOLBL3MBTL1
SCHEMBL20171641 0.76 ODC1 (0.31) HTR1BCHRM1
SCHEMBL18652062 0.76 CHRM1 (0.30) CHRM1
SCHEMBL12465210 0.73
SCHEMBL7507371 0.73
SCHEMBL13285300 0.73
SCHEMBL8236244 0.73
SCHEMBL18469593 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3677602-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2020-07-08 EP disclosed