Sugi Predict

Sugi Predict / Compounds / SCHEMBL221982

SCHEMBL221982

SCHEMBL221982

O=Cc1nc2ccccc2s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB8 P28062 1/20 0.53
▸ PSMB5 P28074 1/20 0.53
▸ CA12 O43570 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA4 P22748 1/20 0.52
▸ CA7 P43166 1/20 0.52
▸ CA14 Q9ULX7 1/20 0.52
▸ RAB9A P51151 7/20 0.51
▸ MAPT P10636 7/20 0.51
▸ MEN1 O00255 6/20 0.51
▸ KMT2A Q03164 6/20 0.51
▸ NPC1 O15118 3/20 0.51
▸ TDP1 Q9NUW8 2/20 0.51
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ CASP3 P42574 1/20 0.51
▸ SENP7 Q9BQF6 1/20 0.51
▸ ALDH1A1 P00352 6/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954323 1.00 PSMB8 (0.53) PSMB8PSMB5CA12CA1CA2
SCHEMBL7465202 0.81 MAPT (0.54) PSMB8PSMB5CA12CA1CA2
SCHEMBL7465197 0.81 MAPT (0.54) PSMB8PSMB5CA12CA1CA2
SCHEMBL31074949 0.81 MAPT (0.54) PSMB8PSMB5CA12CA1CA2
SCHEMBL288476 0.81 MAPT (0.57) PSMB8PSMB5RAB9AMAPTMEN1
SCHEMBL8718230 0.81 SNCA (0.57) RAB9AMAPTMEN1KMT2ANPC1
SCHEMBL6606618 0.81 MEN1 (0.67) RAB9AMAPTMEN1KMT2ANPC1
SCHEMBL6606615 0.81 MEN1 (0.67) RAB9AMAPTMEN1KMT2ANPC1
SCHEMBL30733182 0.81 MEN1 (0.67) RAB9AMAPTMEN1KMT2ANPC1
SCHEMBL8718231 0.81 SNCA (0.57) RAB9AMAPTMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1015 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978936-B Light radiation heat-preservation heat-insulation decorative plate for outer wall and preparation method thereof 广州米伽新材料科技有限公司 2025-06-24 — — CN claimed
CN-119978936-A Light radiation heat-preservation heat-insulation decorative plate for outer wall and preparation method thereof 广州米伽新材料科技有限公司 2025-05-13 — — CN claimed
US-20250074938-A1 CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-03-06 — — US claimed
CN-119425786-A Thiazole ring modification C3N4/C3N5Heterojunction photocatalyst and preparation method and application thereof 中国矿业大学 2025-02-14 — — CN claimed
CN-118994580-A High refractive index polymer material containing sulfur and selenium element and preparation method thereof 吉林大学 2024-11-22 — — CN claimed
CN-118702719-A Preparation method of high-purity methyldichlorosilane 武汉新硅科技潜江有限公司 2024-09-27 — — CN claimed
CN-118661738-A Efficient sterilizing algicide for treating circulating water and preparation method thereof 湖北海翔科技有限公司 2024-09-20 — — CN claimed
CN-115819371-B Preparation method of benzothiazole-2-formaldehyde and derivatives thereof 新疆师范大学 2024-05-14 — — CN claimed
CN-117362162-A Preparation method of carbonyl compound 中国科学院大连化学物理研究所 2024-01-09 — — CN claimed
CN-113980039-B Photothermal agent and preparation method and application thereof 杭州师范大学 2023-08-18 — — CN claimed
US-6710056-B2 PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE AN EXCELLENT ANTAGONISTIC EFFECT AGAINST ACTIVATED BLOOD COAGULATION FACTOR VII. AJINOMOTO CO., INC. (JP) 2004-03-23 — — US claimed
EP-1397340-A2 CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2004-03-17 — — EP claimed
US-20030109547-A1 Amidinophenylpyruvic acid derivatives AJINOMOTO CO. INC (JP) 2003-06-12 — — US claimed
WO-2002098850-A2 CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2002-12-12 — — WO claimed
EP-1236712-A1 AMIDINOPHENYLPYRUVIC ACID DERIVATIVE Ajinomoto Co., Inc. (JP) 2002-09-04 — — EP claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 — — US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 — — US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 — — US claimed
US-4066752-A 1-Desamino-1-hydroxy and 1-desamino-1-epi-hydroxy-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols; 1-desamino-1-oxo-4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitols, intermediates and use as antibacterial agents SCHERING CORPORATION (US) 1978-01-03 — — US claimed
US-4053468-A PROCESS FOR PREPARING 7-OXO CEPHALOSPORINS AND 6-OXO PENICILLINS SMITHKLINE CORPORATION (US) 1977-10-11 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074938-A1 CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES ACE, TMPRSS2, ACE2 PSMB8 1146/4885PSMB5 1467/4885CA12 606/4885
US-20030109547-A1 Amidinophenylpyruvic acid derivatives HABP2, F2, F7 PSMB8 3381/4885PSMB5 4560/4885CA12 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.