Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31074949 | 1.00 | MAPT (0.54) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL7465197 | 1.00 | MAPT (0.54) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL6002823 | 0.82 | MAPT (0.54) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL7463297 | 0.81 | SNCA (0.38) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL7463299 | 0.81 | SNCA (0.38) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL221982 | 0.81 | PSMB8 (0.53) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL29954323 | 0.81 | PSMB8 (0.53) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11776645 | 0.81 | MAPT (0.57) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL28820669 | 0.81 | MAPT (0.56) | MAPTRAB9AKMT2AMEN1TDP1 | |
| SCHEMBL29881859 | 0.81 | MAPT (0.56) | MAPTRAB9AKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |