⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755823 | 0.77 | — | — | |
| SCHEMBL4723061 | 0.77 | — | — | |
| SCHEMBL10073308 | 0.77 | — | — | |
| SCHEMBL16727770 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL22652960 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL12590944 | 0.73 | — | — | |
| SCHEMBL28901011 | 0.73 | MAPK1 (0.36) | — | |
| SCHEMBL12269633 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL9975249 | 0.71 | SLC6A4 (0.32) | — | |
| SCHEMBL3629332 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129910-B2 | Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-09-28 | — | — | US | disclosed |
| US-20200215206-A1 | SPECIFIC CONJUGATION LINKERS, SPECIFIC IMMUNOCONJUGATES THEREOF, METHODS OF MAKING AND USES SUCH CONJUGATES THEREOF | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2020-07-09 | — | — | US | disclosed |