Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37106799 | 1.00 | LMNA (0.42) | LMNAKDM4EPOLBMAPTCA12 | |
| SCHEMBL7165490 | 1.00 | LMNA (0.42) | LMNAKDM4EPOLBMAPTCA12 | |
| SCHEMBL26623041 | 0.93 | BRD3 (0.42) | LMNAKDM4EPOLBMAPTBRD3 | |
| SCHEMBL24728401 | 0.89 | LMNA (0.43) | LMNAKDM4EPOLBMAPTCA12 | |
| SCHEMBL30138591 | 0.89 | LMNA (0.43) | LMNAKDM4EPOLBMAPTCA12 | |
| SCHEMBL26471064 | 0.88 | KDM4E (0.36) | LMNAKDM4EPOLBMAPTCRBN | |
| SCHEMBL30841804 | 0.88 | KDM4E (0.42) | LMNAKDM4EPOLBMAPTCA12 | |
| SCHEMBL30221837 | 0.87 | BRD3 (0.31) | LMNAKDM4EPOLBMAPTBRD3 | |
| SCHEMBL30221744 | 0.87 | BRD3 (0.31) | LMNAKDM4EPOLBMAPTBRD3 | |
| SCHEMBL26623051 | 0.87 | BRD3 (0.31) | LMNAKDM4EPOLBMAPTBRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677568-A1 | NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-07-08 | — | — | EP | disclosed |