Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190351 | 1.00 | PARP1 (0.48) | PARP1PARP2DDB1CRBNHTR2C | |
| SCHEMBL8530446 | 0.90 | PARP1 (0.46) | PARP1PARP2DDB1CRBNHTR2C | |
| SCHEMBL22201150 | 0.83 | DDB1 (0.47) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL14457994 | 0.83 | DDB1 (0.47) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL3600762 | 0.81 | HTR2C (0.51) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30640419 | 0.81 | HTR2C (0.51) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3600768 | 0.81 | HTR2C (0.51) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23878342 | 0.80 | TDP1 (0.46) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL22039449 | 0.80 | TDP1 (0.46) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL7237762 | 0.80 | TDP1 (0.46) | DDB1CRBNPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |