Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14457994 | 1.00 | DDB1 (0.47) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL12326005 | 0.84 | TNKS2 (0.46) | DDB1CRBNTNKS2TNKSPARP3 | |
| SCHEMBL22201144 | 0.83 | PARP1 (0.48) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL22190351 | 0.83 | PARP1 (0.48) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL22201146 | 0.80 | ALDH1A1 (0.54) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL14458009 | 0.80 | ALDH1A1 (0.54) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL14458020 | 0.80 | PDE4A (0.43) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL23878342 | 0.77 | TDP1 (0.46) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL22190402 | 0.77 | PDE4A (0.44) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL22201140 | 0.77 | PDE4A (0.44) | DDB1CRBNPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |