SCHEMBL22201155

SCHEMBL22201155

CCCCCCCC/C=C/CCCC[C@@H]1CCC(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
FAAH O00519 3/20 0.41
TRPV1 Q8NER1 1/20 0.41
TSHR P16473 1/20 0.40
MGLL Q99685 2/20 0.40
CYP1A2 P05177 3/20 0.40
EPHX2 P34913 1/20 0.39
S1PR2 O95136 1/20 0.37
S1PR4 O95977 1/20 0.37
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
S1PR5 Q9H228 1/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22201158 1.00 ALDH1A1 (0.46) ALDH1A1L3MBTL1FAAHTRPV1TSHR
SCHEMBL5475404 0.91 ALDH1A1 (0.39) ALDH1A1L3MBTL1FAAHTRPV1TSHR
SCHEMBL5175881 0.91 ALDH1A1 (0.53) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
SCHEMBL22190342 0.91 ALDH1A1 (0.53) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
SCHEMBL5872353 0.91 ALDH1A1 (0.53) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
SCHEMBL9646435 0.91 ALDH1A1 (0.53) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
SCHEMBL22201153 0.91 ALDH1A1 (0.53) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
SCHEMBL8051534 0.91 ALDH1A1 (0.53) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
SCHEMBL3503763 0.89 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP1A2S1PR2S1PR4
Hydrochloric Acid SCHEMBL5493851 0.89 ALDH1A1 (0.38) ALDH1A1L3MBTL1FAAHTRPV1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020141734-A1 METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR 기초과학연구원 2020-07-09 WO disclosed