Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18341407 | 1.00 | DDB1 (0.44) | DDB1CRBNPOLBPDE4APDE4B | |
| SCHEMBL19471140 | 0.84 | POLB (0.47) | POLBKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL3733164 | 0.80 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL432587 | 0.80 | KDM4E (0.44) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL8530679 | 0.80 | KMT2A (0.49) | DDB1CRBNPOLBKDM4EALDH1A1 | |
| SCHEMBL24282883 | 0.80 | MDM2 (0.61) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL10400359 | 0.80 | CRBN (0.59) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL22201147 | 0.79 | PDE4A (0.44) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL4142288 | 0.79 | PDE4A (0.44) | DDB1CRBNPDE4APDE4BPDE4C | |
| SCHEMBL482061 | 0.79 | PDE4A (0.44) | DDB1CRBNPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |