Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269308 | 1.00 | GBA1 (0.47) | GBA1MAPK1HDAC8DDB1CRBN | |
| SCHEMBL1760901 | 0.82 | GBA1 (0.58) | GBA1HDAC8DDB1CRBNCYP19A1 | |
| SCHEMBL12040400 | 0.82 | CRBN (0.53) | GBA1HDAC8DDB1CRBNCYP19A1 | |
| SCHEMBL11347478 | 0.82 | ALDH1A1 (0.40) | — | |
| SCHEMBL1269213 | 0.82 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL11350603 | 0.82 | CMA1 (0.46) | — | |
| SCHEMBL11359163 | 0.81 | HDAC8 (0.50) | GBA1HDAC8DDB1CRBNCYP19A1 | |
| SCHEMBL11352361 | 0.80 | CMA1 (0.48) | — | |
| SCHEMBL25698328 | 0.80 | DDB1 (0.46) | GBA1HDAC8DDB1CRBN | |
| SCHEMBL25698327 | 0.80 | GBA1 (0.50) | GBA1HDAC8DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026098567-A1 | MACROCYCLIC COMPOUNDS AND USE THEREOF | 微境生物医药科技(上海)有限公司 | 2026-05-15 | — | — | WO | disclosed |
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |