Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201428 | 0.91 | ALDH1A1 (0.81) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201338 | 0.89 | ABCG2 (0.76) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201361 | 0.86 | ABCG2 (1.00) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201344 | 0.85 | ALDH1A1 (0.72) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL1083764 | 0.85 | ABCG2 (1.00) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201663 | 0.84 | ALDH1A1 (0.70) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201579 | 0.82 | ABCG2 (0.85) | ABCG2ABCB1MEN1KMT2AKDM4E | |
| SCHEMBL1063510 | 0.82 | ABCG2 (0.91) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201677 | 0.82 | ALDH1A1 (0.67) | ABCG2ABCB1MEN1KMT2AABCC1 | |
| SCHEMBL22201440 | 0.81 | ABCG2 (0.74) | ABCG2ABCB1MEN1KMT2AABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |