Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.58 |
| ▸ | LATS1 | O95835 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.58 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201350 | 0.92 | ABCG2 (0.58) | ABCG2MEN1KMT2AABCC1LATS1 | |
| SCHEMBL22201356 | 0.85 | HPGD (0.55) | ABCG2LATS1ABCB1PRKD1KDM4E | |
| SCHEMBL13319636 | 0.84 | ABCG2 (0.58) | ABCG2MEN1KMT2AABCC1ABCB1 | |
| SCHEMBL22201616 | 0.83 | ABCG2 (0.53) | ABCG2MEN1KMT2AABCC1LATS1 | |
| SCHEMBL22201341 | 0.83 | PRKD1 (0.66) | ABCG2MEN1KMT2AABCC1ABCB1 | |
| SCHEMBL22201395 | 0.81 | FGFR2 (0.55) | ABCG2LATS1ABCB1PRKD1KDM4E | |
| SCHEMBL22201348 | 0.81 | PRKD1 (0.60) | ABCG2LATS1ABCB1PRKD1KDM4E | |
| SCHEMBL22201354 | 0.79 | HPGD (0.55) | ABCG2ABCB1PRKD1KDM4ELMNA | |
| SCHEMBL22201351 | 0.79 | ABCG2 (0.54) | ABCG2MEN1KMT2AABCC1ABCB1 | |
| SCHEMBL22201353 | 0.79 | ABCG2 (0.54) | ABCG2MEN1KMT2AABCC1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |