Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 11/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280853 | 0.81 | SYK (0.73) | SYK | |
| SCHEMBL3280663 | 0.81 | SYK (0.71) | SYKNPC1KDM4EALDH1A1MAPT | |
| SCHEMBL11379518 | 0.81 | SYK (0.68) | PRKCHPRKCESYKNR4A2NPC1 | |
| SCHEMBL3280921 | 0.79 | CDC7 (0.48) | SYKALDH1A1 | |
| SCHEMBL22201436 | 0.78 | PRKCH (0.52) | PRKCHPRKCEMAPK1NPC1DHODH | |
| SCHEMBL14902607 | 0.78 | MEN1 (0.45) | SYKNPC1MAPT | |
| SCHEMBL7265445 | 0.78 | SYK (0.61) | SYK | |
| SCHEMBL523788 | 0.78 | SYK (0.50) | SYKNPC1DHODHKDM4EALDH1A1 | |
| SCHEMBL12385924 | 0.77 | DHODH (0.51) | SYKMAPK1METAP1NPC1DHODH | |
| SCHEMBL12385928 | 0.77 | SYK (0.49) | SYKMAPK1METAP1NPC1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |