Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786133 | 0.87 | MEN1 (0.55) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL31388225 | 0.87 | MEN1 (0.55) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3325621 | 0.82 | PRKCD (0.52) | PRKCHPRKCECYP1A2 | |
| SCHEMBL14727429 | 0.81 | CYP11B1 (0.57) | ALDH1A1KDM4ECYP2C9CYP3A4CYP1A2 | |
| SCHEMBL4767456 | 0.81 | AGTR1 (0.45) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL7258823 | 0.81 | CYP19A1 (0.47) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL4766591 | 0.80 | TOP1 (0.44) | MAPTCYP2C9CYP3A4NPC1CYP1A2 | |
| SCHEMBL7259697 | 0.79 | TNF (0.47) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8295491 | 0.79 | PRKCH (0.52) | PRKCHPRKCEMAPK1ALDH1A1KDM4E | |
| SCHEMBL22201437 | 0.78 | PRKCH (0.56) | PRKCHPRKCEMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |