Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201700 | 0.76 | GLA (0.47) | NPC1RAB9AKMT2AEPHX2CYP3A4 | |
| SCHEMBL14963198 | 0.72 | MC4R (0.62) | MEN1KMT2ACYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL9080 | 0.69 | GAA (0.66) | MEN1KMT2AHTTEPHX2CYP3A4 | |
| SCHEMBL20919864 | 0.69 | TSHR (0.65) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL13118269 | 0.68 | RAB9A (0.97) | NPC1RAB9AMEN1KMT2AEPHX2 | |
| SCHEMBL23004983 | 0.68 | RAB9A (0.73) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL13483850 | 0.68 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL3087061 | 0.67 | GAA (0.73) | RAB9AMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL14724834 | 0.67 | RAB9A (1.00) | NPC1RAB9AMEN1KMT2AEPHX2 | |
| SCHEMBL770934 | 0.67 | CYP3A4 (0.87) | MEN1KMT2AHTTEPHX2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216670-A1 | THERMOSETTING SILICON-CONTAINING COMPOUND, COMPOSITION FOR FORMING A SILICON-CONTAINING FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |