Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 4/20 | 0.37 |
| ▸ | SNCA | P37840 | 4/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201813 | 0.91 | APP (0.40) | ENPP2APPSNCAESRRAKDM4E | |
| SCHEMBL22201823 | 0.90 | APP (0.38) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL28377336 | 0.90 | APP (0.38) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL30426742 | 0.90 | APP (0.38) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL20603140 | 0.90 | APP (0.38) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL22201850 | 0.90 | APP (0.38) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL22201854 | 0.89 | APP (0.37) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL22201855 | 0.89 | APP (0.37) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL20603154 | 0.89 | APP (0.39) | ENPP2APPSNCARPS6KA3JAK3 | |
| SCHEMBL28380649 | 0.89 | APP (0.39) | ENPP2APPSNCARPS6KA3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142413-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-09 | — | — | WO | disclosed |