SCHEMBL20603154

SCHEMBL20603154

N#C/C(=C\c1cn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nccc(Cl)c12)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 4/20 0.39
▸ SNCA P37840 4/20 0.39
▸ ENPP2 Q13822 2/20 0.38
▸ PTGDR2 Q9Y5Y4 1/20 0.37
▸ PTGES O14684 2/20 0.37
▸ RPS6KA3 P51812 1/20 0.34
▸ JAK3 P52333 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ ESRRA P11474 1/20 0.34
▸ MAPT P10636 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ EGFR P00533 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28380649 1.00 APP (0.39) APPSNCAENPP2PTGDR2PTGES
SCHEMBL26552410 0.94 PTGDR2 (0.37) APPSNCAENPP2PTGDR2PTGES
SCHEMBL22201823 0.90 APP (0.38) APPSNCAENPP2PTGDR2PTGES
SCHEMBL30426742 0.90 APP (0.38) APPSNCAENPP2PTGDR2PTGES
SCHEMBL20603140 0.90 APP (0.38) APPSNCAENPP2PTGDR2PTGES
SCHEMBL22201850 0.90 APP (0.38) APPSNCAENPP2PTGDR2PTGES
SCHEMBL28377336 0.90 APP (0.38) APPSNCAENPP2PTGDR2PTGES
SCHEMBL22201854 0.89 APP (0.37) APPSNCAENPP2PTGDR2PTGES
SCHEMBL22201855 0.89 APP (0.37) APPSNCAENPP2PTGDR2PTGES
SCHEMBL22201814 0.89 ENPP2 (0.38) APPSNCAENPP2PTGESRPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036586-A Compositions and methods for modulating hair growth 加利福尼亚大学董事会 2026-05-15 — — CN disclosed
US-20250304579-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-10-02 — — US disclosed
US-12227503-B2 Compositions and methods for modulating hair growth THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-18 — — US disclosed
US-20240025895-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-01-25 — — US disclosed
US-20240025895-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-01-25 — — US disclosed
US-11787804-B2 Compositions and methods for modulating hair growth THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-17 — — US disclosed
US-11787804-B2 Compositions and methods for modulating hair growth THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-17 — — US disclosed
CN-116120314-A Compositions and methods for modulating hair growth 加利福尼亚大学董事会 2023-05-16 — — CN disclosed
US-20230114220-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-04-13 — — US disclosed
US-20230114220-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-04-13 — — US disclosed
US-20220048908-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-02-17 — — US disclosed
EP-3906240-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH The Regents of the University of California (US) 2021-11-10 — — EP disclosed
WO-2021127482-A1 SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH THE REGENT OF THE UNIVERSITY OFCALIFORNIA (US) 2021-06-24 — — WO disclosed
WO-2020142413-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-07-09 — — WO disclosed
WO-2020142413-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-07-09 — — WO disclosed
US-20200157093-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-05-21 — — US disclosed
US-20200157093-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-05-21 — — US disclosed
EP-3644989-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH The Regents of the University of California (US) 2020-05-06 — — EP disclosed
WO-2019006359-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-01-03 — — WO disclosed
WO-2019006359-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-01-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230114220-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885
US-20200157093-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885
US-20250304579-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885
US-20220048908-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885
US-11787804-B2 Compositions and methods for modulating hair growth PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885
US-20240025895-A1 COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885
US-12227503-B2 Compositions and methods for modulating hair growth PC, FH, SLC25A1 APP 2641/4885SNCA 4842/4885ENPP2 2416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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