Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945955 | 0.86 | ATM (0.50) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL28499654 | 0.85 | ATM (0.49) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL22409416 | 0.85 | PLA2G10 (0.50) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL22409417 | 0.85 | PLA2G10 (0.50) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL22203002 | 0.84 | ATM (0.48) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL7321063 | 0.84 | ATM (0.64) | ATMPPARGPPARAPPARDAPP | |
| SCHEMBL22409489 | 0.84 | ATM (0.48) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL22202987 | 0.84 | ATM (0.48) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL19014888 | 0.84 | ATM (0.48) | ATMMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL9404273 | 0.83 | MTNR1A (0.64) | ATMMTNR1AMTNR1BPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140956-A1 | PROCESS FOR PREPARING SULFONAMIDE COMPOUNDS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2020-07-09 | — | — | WO | disclosed |