Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907772 | 0.89 | GLS (0.73) | GLS | |
| SCHEMBL29753256 | 0.88 | GLS (0.77) | GLS | |
| SCHEMBL17419978 | 0.88 | GLS (0.77) | GLS | |
| SCHEMBL22203593 | 0.88 | GLS (0.75) | GLS | |
| SCHEMBL29752733 | 0.87 | GLS (0.77) | GLS | |
| SCHEMBL17420020 | 0.87 | GLS (0.77) | GLS | |
| SCHEMBL17419857 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL17412044 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL29752986 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL29753079 | 0.83 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677579-A1 | HETEROCYCLIC GLS1 INHIBITORS | Board of Regents, The University of Texas System (US) | 2020-07-08 | — | — | EP | disclosed |