Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HLCS | P50747 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119910 | 1.00 | CYP1A2 (0.62) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL4072508 | 0.98 | CYP1A2 (0.65) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL3688744 | 0.92 | CYP1A2 (0.56) | CYP1A2ALDH1A1TSHRPPARGPRKCA | |
| SCHEMBL442643 | 0.83 | CYP1A2 (0.46) | CYP1A2ALDH1A1TSHRPPARGKMT2A | |
| SCHEMBL2690939 | 0.81 | CYP1A2 (0.53) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL19976638 | 0.81 | CYP1A2 (0.53) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL6707183 | 0.81 | CYP1A2 (0.53) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL664978 | 0.81 | CYP1A2 (0.69) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL6662416 | 0.81 | CYP1A2 (0.69) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 | |
| SCHEMBL28296028 | 0.81 | CYP1A2 (0.69) | CYP1A2ALDH1A1TSHRPPARGL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053433-A1 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-02-28 | — | — | US | claimed |
| EP-2521446-A2 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | The University of North Carolina At Chapel Hill (US) | 2012-11-14 | — | — | EP | claimed |
| WO-2011085000-A2 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-07-14 | — | — | WO | claimed |
| WO-2014008159-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS FOR TREATMENT OF TAMOXIFEN RESISTANT TUMORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-01-09 | — | — | WO | disclosed |
| WO-2014008159-A1 | SELECTIVE ESTROGEN RECEPTOR DEGRADERS FOR TREATMENT OF TAMOXIFEN RESISTANT TUMORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-01-09 | — | — | WO | disclosed |
| US-20130053433-A1 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053433-A1 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-02-28 | — | — | US | disclosed |
| EP-2521446-A2 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | The University of North Carolina At Chapel Hill (US) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011085000-A2 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053433-A1 | FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS | FFAR2, FASN, FFAR4 | CYP1A2 384/4885ALDH1A1 288/4885TSHR 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.