Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216322 | 0.85 | CNR2 (0.69) | KDM4ECNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL2212614 | 0.83 | CNR2 (0.56) | KDM4ECNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL2215683 | 0.82 | CYP19A1 (0.57) | KDM4ECNR2ALDH1A1KMT2AGABRP | |
| SCHEMBL13415776 | 0.81 | ALDH1A1 (0.64) | KDM4ECNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL27987637 | 0.80 | CNR2 (0.53) | KDM4ECNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL2216672 | 0.79 | CNR2 (0.70) | CNR2ALDH1A1HPGD | |
| SCHEMBL2214890 | 0.78 | CNR2 (0.46) | KDM4ECNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL600250 | 0.78 | CNR2 (0.76) | CNR2ALDH1A1HPGD | |
| SCHEMBL2215826 | 0.78 | CNR2 (0.56) | KDM4ECNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL27899823 | 0.77 | CNR2 (0.74) | CNR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | claimed |