Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316181 | 0.87 | MAPT (0.39) | GRM5NPC1RAB9AHCAR1PLAU | |
| SCHEMBL29444927 | 0.80 | SLC5A1 (0.48) | NPC1RAB9AL3MBTL1ELANEMAPT | |
| SCHEMBL29571602 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9AHCAR1TDP1L3MBTL1 | |
| SCHEMBL15639208 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9AHCAR1TDP1L3MBTL1 | |
| SCHEMBL27344914 | 0.77 | MAPT (0.41) | GRM5NPC1RAB9AHCAR1MAPT | |
| SCHEMBL2510446 | 0.76 | IDO1 (0.42) | RAB9ATDP1L3MBTL1TSHRMAPT | |
| SCHEMBL15754580 | 0.75 | ALDH1A1 (0.54) | L3MBTL1MAPTAKR1C3AKR1C1ALDH1A1 | |
| SCHEMBL1462240 | 0.75 | MAPT (0.58) | L3MBTL1TSHRMAPTALDH1A1CYP1A2 | |
| SCHEMBL6448373 | 0.74 | KMT2A (0.50) | NPC1RAB9AHCAR1TDP1L3MBTL1 | |
| SCHEMBL3383807 | 0.74 | ALDH1A1 (0.45) | MAPTAKR1C3AKR1C1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262827-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | BIOARDIS LLC (US) | 2020-08-20 | — | — | US | disclosed |
| EP-3680236-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | Bioardis LLC (US) | 2020-07-15 | — | — | EP | disclosed |
| CN-1050382-A | Pyrazole derivatives and preparation method thereof and medicinal compositions | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-04-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262827-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | FGFR4, FGFR1, FGFR3 | GRM5 3181/4885NPC1 2095/4885RAB9A 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.