SCHEMBL2220484

SCHEMBL2220484

Cc1c(CO)cc(CO)c(O)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.48
KDM4E B2RXH2 3/20 0.40
CASP6 P55212 1/20 0.40
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 1/20 0.38
PDXK O00764 2/20 0.36
LMNA P02545 3/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
AOX1 Q06278 1/20 0.33
MAOA P21397 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
KLF10 Q13118 1/20 0.33
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
PDE4A P27815 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4064855 0.91 SHBG (0.50) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL31612189 0.91 SHBG (0.50) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL27502458 0.85 SHBG (0.48) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL18541219 0.84 SHBG (0.39) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL5608947 0.83 SHBG (0.52) SHBGKDM4ECASP6ALDH1A1HPGD
Methane SCHEMBL27819860 0.81 SHBG (0.45) SHBGKDM4ECASP6ALDH1A1HPGD
Methane SCHEMBL2221487 0.81 SHBG (0.45) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL17427509 0.79 SHBG (0.44) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL10451916 0.76 KDM4E (0.44) SHBGKDM4ECASP6ALDH1A1HPGD
SCHEMBL12201590 0.75 KDM4E (0.48) SHBGKDM4ECASP6ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-9122183-B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2015-09-01 US disclosed
US-9081353-B2 Cleaner, and process cartridge and image forming apparatus using the cleaner RICOH COMPANY, LTD. (JP) 2015-07-14 US disclosed
CN-103926820-A Cleaner, and process cartridge and image forming apparatus using the cleaner RICOH CO LTD 2014-07-16 CN disclosed
US-20140193172-A1 CLEANER, AND PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS USING THE CLEANER RICOH COMPANY, LTD. (JP) 2014-07-10 US disclosed
US-20130244150-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
US-20110173807-A1 DISPERSION FOR DISPOSING FINE PARTICLE AT PREDETERMINED POINT ON SUBSTRATE BY INK-JET PRINTING NATOCO CO., LTD. (JP) 2011-07-21 US disclosed