SCHEMBL2220656

SCHEMBL2220656

COC(=O)COCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1335833 0.83 TSHR (0.56)
SCHEMBL831512 0.80
SCHEMBL13241991 0.78 TSHR (0.50)
SCHEMBL6463788 0.78 TSHR (0.50)
SCHEMBL18906770 0.77 TSHR (0.39)
SCHEMBL18906900 0.77 TSHR (0.39)
SCHEMBL26699205 0.77 TSHR (0.46)
SCHEMBL195069 0.76
Ethylene Glycol SCHEMBL9359880 0.76 TSHR (0.48)
SCHEMBL10402192 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415272-B2 Quinoline derivatives and their use as fungicides SYNGENTA CROP PROTECTION LLC (US) 2013-04-09 US disclosed
US-20120283216-A1 FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY 2012-11-08 US disclosed
EP-2516385-A2 FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES E. I. du Pont de Nemours and Company (US) 2012-10-31 EP disclosed
US-8288505-B2 Functionalized diphenolics and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-10-16 US disclosed
WO-2012087372-A1 FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
US-20110223254-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2011-09-15 US disclosed
WO-2011087837-A9 FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-09 WO disclosed
WO-2011087837-A2 FUNGICIDAL 2-(BICYCLIC ARYLOXY)CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 WO disclosed
US-20100280068-A1 QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-11-04 US disclosed
EP-2231614-A2 QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES Syngenta Participations AG (CH) 2010-09-29 EP disclosed
US-20100113513-A1 QUINOLINE DERIVATIVES AS FUNGICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-05-06 US disclosed
EP-2139324-A1 QUINOLINE DERIVATIVES AS FUNGICIDES Syngeta Participations AG (CH) 2010-01-06 EP disclosed
WO-2009087098-A2 QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-07-16 WO disclosed
WO-2008110355-A1 QUINOLINE DERIVATIVES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-09-18 WO disclosed
US-7172894-B2 Reductase gene and use of the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2007-02-06 US disclosed
US-20040171119-A1 Reductase gene and use of the same SUMITOMO CHEMICAL COMPANY, LIMITED 2004-09-02 US disclosed
EP-1452588-A1 Reductase gene and use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-09-01 EP disclosed
US-4223162-A Ether carboxylates containing three carboxylate groups MONSANTO COMPANY (US) 1980-09-16 US disclosed