⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70438 | 0.81 | — | — | |
| SCHEMBL71151 | 0.81 | — | — | |
| SCHEMBL1958871 | 0.74 | — | — | |
| SCHEMBL23249833 | 0.74 | — | — | |
| SCHEMBL13482301 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL26921992 | 0.72 | AOC1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL30612308 | 0.72 | AOC1 (0.32) | — | |
| SCHEMBL21598602 | 0.70 | — | — | |
| SCHEMBL20487618 | 0.70 | — | — | |
| SCHEMBL2220872 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| EP-3908579-B1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH INC (US) | 2023-12-27 | — | — | EP | disclosed |
| US-20220089568-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. | 2022-03-24 | — | — | US | disclosed |
| US-20220081422-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. | 2022-03-17 | — | — | US | disclosed |
| EP-3920922-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3908579-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Janssen Biotech, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |
| CN-113574054-A | Dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113453680-A | Dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020161663-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020144638-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. (US) | 2020-07-16 | — | — | WO | disclosed |