SCHEMBL2220747

SCHEMBL2220747

CC(C)(c1ccc(OC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1)c1ccc(OC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NPSR1 Q6W5P4 2/20 0.41
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
PRSS1 P07477 2/20 0.39
ACR P10323 2/20 0.39
AR P10275 2/20 0.38
ELANE P08246 2/20 0.38
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 2/20 0.38
KIF11 P52732 1/20 0.37
HTT P42858 2/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25986436 0.92 MAPT (0.41) MAPTTDP1L3MBTL1NPSR1ALDH1A1
SCHEMBL12442868 0.85 HSD17B10 (0.38) MAPTTDP1L3MBTL1NPSR1ALDH1A1
SCHEMBL12442872 0.83 ELANE (0.42) MAPTTDP1L3MBTL1NPSR1ALDH1A1
SCHEMBL24289734 0.81 ESR1 (0.41) MAPTTDP1L3MBTL1NPSR1ALDH1A1
SCHEMBL12442878 0.80 MAPT (0.38) MAPTTDP1L3MBTL1NPSR1ALDH1A1
SCHEMBL532804 0.80 LMNA (0.53) MAPTL3MBTL1NPSR1ALDH1A1CA1
SCHEMBL10236283 0.80 MAPT (0.51) MAPTTDP1L3MBTL1NPSR1ALDH1A1
SCHEMBL2356535 0.80 ELANE (0.44) MAPTALDH1A1CA1CA2ELANE
SCHEMBL2833915 0.80 KMT2A (0.49) MAPTALDH1A1CA1CA2KMT2A
SCHEMBL12442882 0.79 MAPT (0.37) MAPTTDP1L3MBTL1NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-03 US disclosed
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-03 US disclosed
WO-2022075382-A1 ESTER COMPOUND AND RESIN COMPOSITION 味の素株式会社 2022-04-14 WO disclosed
US-8698142-B2 Organic semiconductor element, method of manufacturing organic semiconductor element, electronic device, electronic equipment and insulating layer forming composition SEIKO EPSON CORPORATION (JP) 2014-04-15 US disclosed
EP-1600471-B1 Fluorine-containing compound NIPPON CATALYTIC CHEM IND (JP) 2011-08-24 EP disclosed
US-20110175092-A1 ORGANIC SEMICONDUCTOR ELEMENT, METHOD OF MANUFACTURING ORGANIC SEMICONDUCTOR ELEMENT, ELECTRONIC DEVICE, ELECTRONIC EQUIPMENT AND INSULATING LAYER FORMING COMPOSITION E INK CORPORATION 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AFF4, AFF1, AFF2 MAPT 2274/4885TDP1 3118/4885L3MBTL1 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.