Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.34 | |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 4/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22207651 | 1.00 | AKT1 (0.43) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL28620369 | 0.94 | AKT1 (0.41) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL28624848 | 0.94 | AKT1 (0.41) | AKT1TDP1ATMNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL23113668 | 0.86 | SLC15A2 (0.40) | AKT1NPSR1PTGS1PTGS2MAPT | |
| Trifluoroacetic Acid SCHEMBL23113666 | 0.86 | SLC15A2 (0.40) | AKT1NPSR1PTGS1PTGS2MAPT | |
| SCHEMBL28922741 | 0.86 | AKT1 (0.56) | AKT1TDP1PAX8SSTR2SSTR1 | |
| SCHEMBL28922739 | 0.86 | AKT1 (0.56) | AKT1TDP1PAX8SSTR2SSTR1 | |
| SCHEMBL23113667 | 0.83 | MGLL (0.36) | NPSR1PTGS1PTGS2MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL31441171 | 0.81 | AKT1 (0.44) | AKT1TDP1NPSR1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL31441173 | 0.81 | AKT1 (0.39) | AKT1TDP1ATMNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020145228-A1 | COMPLEX COMPRISING LIGAND AND CEACAM5 ANTIBODY FAB FRAGMENT | アステラス製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |
| WO-2020145227-A1 | COMPLEX COMPRISING LIGAND, SPACER, PEPTIDE LINKER, AND BIOMOLECULE | アステラス製薬株式会社 | 2020-07-16 | — | — | WO | disclosed |