Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442362 | 1.00 | SQOR (0.81) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442270 | 0.90 | SQOR (1.00) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL22215766 | 0.90 | SQOR (1.00) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442301 | 0.89 | SQOR (0.85) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442349 | 0.89 | SQOR (0.85) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL22215890 | 0.89 | SQOR (0.85) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442372 | 0.88 | SQOR (0.83) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442346 | 0.88 | SQOR (0.83) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL22208381 | 0.85 | SQOR (0.78) | SQORALDH1A1GAAMAPK1KDM4E | |
| SCHEMBL29442285 | 0.85 | SQOR (0.78) | SQORALDH1A1GAAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146636-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING HEART FAILURE | DREXEL UNIVERSITY (US) | 2020-07-16 | — | — | WO | claimed |
| WO-2020146636-A1 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING HEART FAILURE | DREXEL UNIVERSITY (US) | 2020-07-16 | — | — | WO | disclosed |