Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.71 |
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL8828009 | 0.96 | MAOB (0.62) | MAOBMAOACYP19A1GFERHTR2A | |
| Aniline SCHEMBL27621609 | 0.93 | MAOB (0.60) | MAOBMAOACYP19A1GFERHTR2A | |
| SCHEMBL5962 | 0.89 | GFER (0.68) | MAOBMAOACYP19A1GFERHTR2A | |
| SCHEMBL29155827 | 0.86 | GFER (0.65) | MAOBMAOACYP19A1GFERHTR2A | |
| 4-Bromoaniline SCHEMBL8828005 | 0.86 | MAOB (0.57) | MAOBMAOACYP19A1GFERHTR2A | |
| Benzenethiol SCHEMBL27943318 | 0.86 | MAOB (0.57) | MAOBMAOACYP19A1GFERHTR2A | |
| Ethylamine SCHEMBL27859952 | 0.84 | GFER (0.62) | MAOBMAOACYP19A1GFERHTR2A | |
| Methylamine SCHEMBL9350485 | 0.84 | TAAR1 (0.55) | MAOBMAOAHTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL4082319 | 0.84 | MAOB (1.00) | MAOBMAOACYP19A1GFERHTR2A | |
| SCHEMBL6546791 | 0.84 | MAOA (0.56) | MAOBMAOAHTR2ACYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10710983-B2 | 2,4-diamino-pyrimidine compounds and method for making and using the compounds | RIGEL PHARMACEUTICALS, INC. (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10710983-B2 | 2,4-diamino-pyrimidine compounds and method for making and using the compounds | IRAK4, IRAK1, IRAK2 | MAOB 2503/4885MAOA 3297/4885CYP19A1 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.