Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25866575 | 1.00 | SPHK1 (0.45) | SPHK1SPHK2PLA2G2CLMNACYP2D6 | |
| SCHEMBL14547023 | 0.98 | PLA2G2C (0.45) | SPHK1SPHK2PLA2G2CLMNACYP2D6 | |
| SCHEMBL21908450 | 0.96 | PLA2G2C (0.42) | SPHK1SPHK2PLA2G2CLMNATP53 | |
| SCHEMBL11331509 | 0.91 | PLA2G2C (0.41) | SPHK1SPHK2PLA2G2C | |
| SCHEMBL17046803 | 0.90 | SPHK1 (0.39) | SPHK1SPHK2PLA2G2CLMNACYP2D6 | |
| SCHEMBL28189421 | 0.89 | SPHK1 (0.39) | SPHK1SPHK2PLA2G2CLMNACYP2D6 | |
| SCHEMBL10546368 | 0.87 | TSHR (0.39) | SPHK1SPHK2PLA2G2CLMNACYP2D6 | |
| SCHEMBL21922525 | 0.86 | PRSS1 (0.34) | SPHK1SPHK2PLA2G2CTP53LAP3 | |
| SCHEMBL13587256 | 0.83 | ADH1B (0.47) | SPHK1SPHK2LMNACYP2D6GMNN | |
| SCHEMBL13725523 | 0.83 | ADH1B (0.47) | SPHK1SPHK2LMNACYP2D6GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711036-B2 | MALT1 inhibitors and uses thereof | MALT1, BCL3, BCL6 | SPHK1 2471/4885SPHK2 3432/4885PLA2G2C 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.