SCHEMBL22209365

SCHEMBL22209365

CC(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)CF

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MALT1 Q9UDY8 4/20 0.64
▸ CMA1 P23946 12/20 0.53
▸ EPHA2 P29317 2/20 0.47
▸ ELANE P08246 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18621052 1.00 MALT1 (0.64) MALT1CMA1EPHA2ELANE
SCHEMBL22811073 1.00 MALT1 (0.64) MALT1CMA1EPHA2ELANE
SCHEMBL18619572 1.00 MALT1 (0.64) MALT1CMA1EPHA2ELANE
SCHEMBL22209378 0.98 MALT1 (0.61) MALT1CMA1EPHA2ELANE
SCHEMBL18619579 0.98 MALT1 (0.61) MALT1CMA1EPHA2ELANE
SCHEMBL22209379 0.97 MALT1 (0.61) MALT1CMA1EPHA2ELANE
SCHEMBL18619548 0.94 MALT1 (0.60) MALT1CMA1EPHA2ELANE
SCHEMBL22209394 0.94 MALT1 (0.60) MALT1CMA1EPHA2ELANE
SCHEMBL22209500 0.94 MALT1 (0.69) MALT1CMA1EPHA2
SCHEMBL18619626 0.94 MALT1 (0.59) MALT1CMA1EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711036-B2 MALT1 inhibitors and uses thereof CORNELL UNIVERSITY (US) 2020-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711036-B2 MALT1 inhibitors and uses thereof MALT1, BCL3, BCL6 MALT1 1/4885CMA1 130/4885EPHA2 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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