Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.64 |
| ▸ | CMA1 | P23946 | 12/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18621052 | 1.00 | MALT1 (0.64) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL22209365 | 1.00 | MALT1 (0.64) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL18619572 | 1.00 | MALT1 (0.64) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL22209378 | 0.98 | MALT1 (0.61) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL18619579 | 0.98 | MALT1 (0.61) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL22209379 | 0.97 | MALT1 (0.61) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL18619548 | 0.94 | MALT1 (0.60) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL22209394 | 0.94 | MALT1 (0.60) | MALT1CMA1EPHA2ELANE | |
| SCHEMBL22209500 | 0.94 | MALT1 (0.69) | MALT1CMA1EPHA2 | |
| SCHEMBL18619626 | 0.94 | MALT1 (0.59) | MALT1CMA1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |