Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 8/20 | 0.58 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22811348 | 0.81 | PREP (0.69) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL22209470 | 0.81 | PREP (0.69) | PREPDPP4FAPDPP7ACE | |
| SCHEMBL27147721 | 0.81 | PREP (0.52) | PREPDPP4FAPDPP7LOXL2 | |
| SCHEMBL32680841 | 0.81 | PREP (0.52) | PREPDPP4FAPDPP7LOXL2 | |
| SCHEMBL22811105 | 0.80 | ACE (0.52) | PREPGPR139TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL22468385 | 0.80 | NPC1 (0.61) | PREPDPP4FAPNPC1GAA | |
| SCHEMBL28661857 | 0.80 | NPC1 (0.61) | PREPDPP4FAPNPC1GAA | |
| SCHEMBL22798165 | 0.79 | CMA1 (0.51) | TAS1R3TAS1R1TAS1R2ACEACE2 | |
| SCHEMBL22209387 | 0.79 | CMA1 (0.51) | TAS1R3TAS1R1TAS1R2ACEACE2 | |
| SCHEMBL22209407 | 0.79 | DPP4 (0.62) | PREPDPP4FAPNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711036-B2 | MALT1 inhibitors and uses thereof | MALT1, BCL3, BCL6 | PREP 1162/4885GPR139 3879/4885CCR2 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.