Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2257511 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2259990 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2218438 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2258838 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2254789 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2256002 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2255838 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2255273 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2255255 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 | |
| SCHEMBL2255062 | 1.00 | DGKA (0.61) | DGKALMNATSHRPAMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873322-A | VIRICIDES, HERPES AND INFLUENZA; LINKED TO CEPHALIN COMPONENTS | CIBA-GEIGY CORPORATION (US) | 1989-10-10 | — | — | US | claimed |
| EP-0074653-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-26 | — | — | EP | claimed |
| EP-0233837-A2 | Saccharide derivatives and method for their preparation | CIBA-GEIGY AG (CH) | 1987-08-26 | — | — | EP | claimed |
| US-4521413-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-04 | — | — | US | claimed |
| EP-0074653-A2 | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and intermediate products for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-03-23 | — | — | EP | claimed |
| CN-118043437-A | Lubricating oil composition, lubricating method and transmission | 出光兴产株式会社 | 2024-05-14 | — | — | CN | disclosed |
| EP-3279292-B1 | LUBRICANT OIL COMPOSITION AND INTERNAL-COMBUSTION-ENGINE FRICTION REDUCTION METHOD | IDEMITSU KOSAN CO (JP) | 2024-05-01 | — | — | EP | disclosed |
| EP-4321164-A2 | COMPOUNDS WITH HIV MATURATION INHIBITORY ACTIVITY | ViiV Healthcare UK (No.5) Limited (GB) | 2024-02-14 | — | — | EP | disclosed |
| US-11883394-B2 | Crystallization process of aripiprazole derivatives in extended release formulations for treatment of schizophrenia | ALKERMES PHARMA IRELAND LIMITED (IE) | 2024-01-30 | — | — | US | disclosed |
| CN-114846125-B | Lubricating oil composition | 出光兴产株式会社 | 2024-01-16 | — | — | CN | disclosed |
| EP-3784349-B1 | COMPOUNDS WITH HIV MATURATION INHIBITORY ACTIVITY | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2023-12-27 | — | — | EP | disclosed |
| CN-112494492-B | Aripiprazole prodrug compositions | 阿尔科姆斯制药爱尔兰有限公司 | 2023-08-25 | — | — | CN | disclosed |
| EP-0335390-A2 | Novel cephalosporin compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-10-04 | — | — | EP | disclosed |
| US-4808620-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0233837-A2 | Saccharide derivatives and method for their preparation | CIBA-GEIGY AG (CH) | 1987-08-26 | — | — | EP | disclosed |
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4443435-A | ANTICARCINOGENS, HYPOTENSIVE AGENTS, HYPERTHYROIDISM | MERCK & CO., INC. (US) | 1984-04-17 | — | — | US | disclosed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0038541-A1 | Novel prodrugs of biologically active agents containing mercapto groups, process for preparing and therapeutically effective composition containing the same | MERCK & CO. INC. (US) | 1981-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11883394-B2 | Crystallization process of aripiprazole derivatives in extended release formulations for treatment of schizophrenia | SAMM50, SLC6A4, RAP2C | DGKA 2825/4885LMNA 4573/4885TSHR 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.