Sulfuric Acid

Sulfuric Acid

SCHEMBL2221135

CC(=O)C(=O)[C@H](N)[C@@H](O)[C@H](O)[C@H](O)CO.O=S(=O)(O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.53
SLCO1B1 Q9Y6L6 1/20 0.53
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDE4A P27815 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL3238445 1.00 USP2 (0.53) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL28138343 0.93 USP2 (0.61) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL28914 0.93 USP2 (0.61) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL21057 0.93 USP2 (0.61) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL149462 0.93 USP2 (0.61) USP2SLCO1B1LMNAL3MBTL1PDE4A
Water SCHEMBL3908933 0.91 USP2 (0.59) USP2SLCO1B1LMNAL3MBTL1PDE4A
Ammonia Solution, Strong SCHEMBL2719059 0.91 USP2 (0.59) USP2SLCO1B1LMNAL3MBTL1PDE4A
Phosphoric Acid SCHEMBL1696409 0.86 USP2 (0.53) USP2SLCO1B1LMNAL3MBTL1PDE4A
Propylamine SCHEMBL13737874 0.84 USP2 (0.52) USP2SLCO1B1LMNAL3MBTL1PDE4A
Galactose SCHEMBL5699454 0.81 USP2 (0.49) USP2SLCO1B1LMNAL3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140246319-A1 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2014-09-04 US claimed
WO-2013009927-A2 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2013-01-17 WO claimed
EP-2516669-A2 ENZYME ASSAYS ON A DROPLET ACTUATOR Advanced Liquid Logic, Inc. (US) 2012-10-31 EP claimed
WO-2011084703-A2 ENZYME ASSAYS ON A DROPLET ACTUATOR ADVANCED LIQUID LOGIC, INC. (US) 2011-07-14 WO claimed
EP-1730600-A1 COMPOSITION AND PROCESS FOR POST-ETCH REMOVAL OF PHOTORESIST AND/OR SACRIFICIAL ANTI-REFLECTIVE MATERIAL DEPOSITED ON A SUBSTRATE Advanced Technology Materials, Inc. (US) 2006-12-13 EP claimed
WO-2005085957-A1 COMPOSITION AND PROCESS FOR POST-ETCH REMOVAL OF PHOTORESIST AND/OR SACRIFICIAL ANTI-REFLECTIVE MATERIAL DEPOSITED ON A SUBSTRATE ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2005-09-15 WO claimed
US-20140162900-A1 METHOD FOR HIGH-THROUGHPUT SCREENING OF COMPOUNDS AND COMBINATIONS OF COMPOUNDS FOR DISCOVERY AND QUANTIFICATION OF ACTIONS, PARTICULARLY UNANTICIPATED THERAPEUTIC OR TOXIC ACTIONS, IN BIOLOGICAL SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-06-12 US disclosed
WO-2013009927-A2 DROPLET ACTUATORS AND TECHNIQUES FOR DROPLET-BASED ASSAYS ADVANCED LIQUID LOGIC, INC. (US) 2013-01-17 WO disclosed
US-20070219161-A1 Preparation Process Of Oligoglycosaminoglycan, And Reducing End Glucuronic Acid Type Oligochondroitin Sulfate And Pharmaceutical Composition Comprising The Same TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-09-20 US disclosed
EP-1784647-A1 METHOD FOR MEASURING DYNAMICS OF SELF-ASSEMBLING SYSTEMS OF BIOLOGICAL MOLECULES IN VIVO AND USES FOR DISCOVERING OR EVALUATING THERAPEUTIC AGENTS Kinemed, Inc. (US) 2007-05-16 EP disclosed
EP-1740620-A1 PREPARATION PROCESS OF OLIGOGLYCOSAMINOGLYCAN, AND REDUCING END GLUCURONIC ACID TYPE OLIGOCHONDROITIN SULFATE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-01-10 EP disclosed
WO-2006017812-A1 METHOD FOR MEASURING DYNAMICS OF SELF-ASSEMBLING SYSTEMS OF BIOLOGICAL MOLECULES IN VIVO AND USES FOR DISCOVERING OR EVALUATING THERAPEUTIC AGENTS KINEMED, INC. (US) 2006-02-16 WO disclosed
WO-2005092931-A1 PREPARATION PROCESS OF OLIGOGLYCOSAMINOGLYCAN, AND REDUCING END GLUCURONIC ACID TYPE OLIGOCHONDROITIN SULFATE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-10-06 WO disclosed
EP-1309314-A2 METHOD OF MAKING TABLETS AND TABLET COMPOSITIONS PRODUCED THEREFROM Rexall Sundown, Inc. (US) 2003-05-14 EP disclosed
WO-2002013793-A2 METHOD OF MAKING TABLETS AND TABLET COMPOSITIONS PRODUCED THEREFROM REXALL SUNDOWN, INC. (US) 2002-02-21 WO disclosed
EP-0855908-A4 1998-08-26 EP disclosed
EP-0855908-A1 DIETARY REGIMEN OF NUTRITIONAL SUPPLEMENTS FOR RELIEF OF SYMPTOMS OF ARTHRITIS Inholtra, Inc. (US) 1998-08-05 EP disclosed
US-5750754-A TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS ZENECA LIMITED (GB) 1998-05-12 US disclosed
WO-1997021434-A1 DIETARY REGIMEN OF NUTRITIONAL SUPPLEMENTS FOR RELIEF OF SYMPTOMS OF ARTHRITIS INHOLTRA, INC. (US) 1997-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219161-A1 Preparation Process Of Oligoglycosaminoglycan, And Reducing End Glucuronic Acid Type Oligochondroitin Sulfate And Pharmaceutical Composition Comprising The Same OSTC, B3GAT3, CSGALNACT1 USP2 1408/4885SLCO1B1 1156/4885LMNA 2246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.