Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.54 |
| ▸ | HTT | P42858 | 10/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 10/20 | 0.54 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NSD2 | O96028 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 10/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 4/20 | 0.54 |
| ▸ | MITF | O75030 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283051 | 0.83 | MAPT (0.72) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL18424314 | 0.82 | CYP19A1 (0.66) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL2244992 | 0.74 | CYP19A1 (0.55) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL12352062 | 0.74 | MAPT (0.50) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL12283197 | 0.74 | MAPT (0.60) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL12352055 | 0.73 | MAPT (0.58) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL20971703 | 0.73 | ALDH1A1 (0.64) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL2243450 | 0.73 | ALDH1A1 (0.64) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL12352053 | 0.72 | KMT2A (0.55) | MAPTHTTMAPK1RAB9AALDH1A1 | |
| SCHEMBL2241338 | 0.72 | ALDH1A1 (0.59) | MAPTHTTMAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328368-B1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITION ASSOCIATED WITH UBIQUITINATION-PROTEASOME SYSTEM | BRIDGENT BIOTECHNOLOGY INC (TW) | 2020-07-15 | — | — | EP | disclosed |