Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932682 | 0.89 | CHRM1 (0.57) | CHRM1PIK3CD | |
| SCHEMBL19932709 | 0.88 | CHRM1 (0.50) | CHRM1 | |
| SCHEMBL19932652 | 0.82 | CHRM1 (0.42) | CHRM1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL22212621 | 0.82 | NPC1 (0.48) | NPC1RAB9A | |
| SCHEMBL22212650 | 0.81 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19932650 | 0.80 | CHRM1 (0.41) | CHRM1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL22212675 | 0.80 | CHRM1 (0.42) | CHRM1NPC1RAB9AALDH1A1POLB | |
| SCHEMBL22212622 | 0.79 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL19932651 | 0.79 | PARP1 (0.42) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL19932681 | 0.79 | CHRM1 (0.64) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |