Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932665 | 0.89 | CHRM1 (0.47) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL22212678 | 0.88 | CHRM1 (0.41) | PARP1CNR1CNR2ABHD12ALDH1A1 | |
| SCHEMBL22212648 | 0.87 | CNR2 (0.48) | CNR1CNR2ABHD12ACKR3 | |
| SCHEMBL19932678 | 0.85 | PARP1 (0.39) | PARP1CNR1CNR2ABHD12TAS1R3 | |
| SCHEMBL22212637 | 0.83 | CHRM1 (0.41) | PARP1CNR1CNR2ABHD12ALDH1A1 | |
| SCHEMBL22212614 | 0.83 | CHRM1 (0.46) | CNR1CNR2ACKR3 | |
| SCHEMBL22212643 | 0.82 | EPHX2 (0.47) | CNR1CNR2 | |
| SCHEMBL19932631 | 0.80 | CHRM1 (0.55) | — | |
| SCHEMBL21545697 | 0.79 | CHRM1 (0.46) | CNR1 | |
| SCHEMBL19932656 | 0.79 | CHRM1 (0.46) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |