Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212614 | 0.94 | CHRM1 (0.46) | CHRM1C3AR1CNR1CNR2ABHD6 | |
| SCHEMBL22212637 | 0.90 | CHRM1 (0.41) | CHRM1CNR1CNR2ABHD12PARP1 | |
| SCHEMBL22212648 | 0.89 | CNR2 (0.48) | CNR1CNR2ABHD12PRKAA2ABHD6 | |
| SCHEMBL19932667 | 0.89 | CHRM1 (0.52) | CHRM1 | |
| SCHEMBL22212676 | 0.88 | PARP1 (0.44) | CNR1CNR2ABHD12PARP1ALDH1A1 | |
| SCHEMBL19932707 | 0.84 | CHRM1 (0.53) | CHRM1 | |
| SCHEMBL22212643 | 0.84 | EPHX2 (0.47) | CNR1CNR2ABHD6 | |
| SCHEMBL22212633 | 0.80 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL19932666 | 0.79 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL22212615 | 0.79 | PARP1 (0.40) | CHRM1CNR1CNR2ABHD12PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |