Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 12/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552816 | 0.90 | SSTR4 (0.40) | SSTR4SSTR1BCHEACHEPTK2 | |
| SCHEMBL16553339 | 0.84 | ACHE (0.46) | SSTR4SSTR1BCHEACHEPTK2 | |
| SCHEMBL16552907 | 0.81 | ACHE (0.46) | CYP19A1BCHEACHECYP27A1CYP24A1 | |
| SCHEMBL16552796 | 0.80 | CYP19A1 (0.44) | CYP19A1BCHEACHECYP27A1CYP24A1 | |
| SCHEMBL16558726 | 0.78 | ACHE (0.48) | SSTR4CYP19A1BCHEACHE | |
| SCHEMBL16552586 | 0.76 | ACHE (0.39) | CYP19A1BCHEACHECYP27A1CYP24A1 | |
| SCHEMBL16552705 | 0.75 | ACHE (0.47) | BCHEACHE | |
| SCHEMBL21887752 | 0.75 | PDE4D (0.45) | BCHEACHE | |
| SCHEMBL16552901 | 0.73 | ACHE (0.48) | BCHEACHE | |
| SCHEMBL16558740 | 0.73 | METAP1 (0.39) | SSTR4CYP19A1BCHEACHECYP27A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3680237-A1 | PROCESS FOR PREPARING SUBSTITUTED 2,3-DIHYDRO-1H-INDEN-1-ONE RETINOIC ACID-RELATED ORPHAN NUCLEAR RECEPTOR ANTAGONISTS FOR TREATING MULTIPLE SCLEROSIS | Arrien Pharmaceuticals LLC (US) | 2020-07-15 | — | — | EP | disclosed |