SCHEMBL22212751

SCHEMBL22212751

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1NC(=O)c1cccc(NC(=O)c2ccccc2)c1F

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.52
RXFP1 Q9HBX9 7/20 0.51
TP53 P04637 1/20 0.51
CYP1A2 P05177 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
POLB P06746 1/20 0.50
HPGD P15428 1/20 0.50
PPARG P37231 3/20 0.48
NR1H4 Q96RI1 2/20 0.48
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196389 0.90 RXFP1 (0.50) GAARXFP1POLBHPGDPPARG
SCHEMBL31187267 0.89 TP53 (0.55) RXFP1TP53CYP1A2CYP2C19HPGD
SCHEMBL29292197 0.86 RXFP1 (0.47) GAARXFP1POLBHPGDPPARG
SCHEMBL31175830 0.85 RXFP1 (0.46) GAARXFP1POLBHPGDPPARG
SCHEMBL21563472 0.85 RXFP1 (0.46) GAARXFP1POLBHPGDPPARG
SCHEMBL31175832 0.85 RXFP1 (0.46) GAARXFP1POLBHPGDPPARG
SCHEMBL16439967 0.84 TP53 (0.45) GAARXFP1TP53CYP1A2MAPT
SCHEMBL1361727 0.84 CYP1A2 (0.50) GAATP53CYP1A2MAPTCYP2C9
SCHEMBL31187263 0.84 NPC1 (0.44) GAARXFP1TP53CYP1A2MAPT
SCHEMBL1766371 0.83 RXFP1 (0.50) RXFP1PPARGNR1H4KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2529620-B1 COMPOSITION FOR CONTROL OF ANIMAL PARASITES, AND METHOD FOR CONTROL OF ANIMAL PARASITES MITSUI CHEMICALS AGRO INC (JP) 2020-07-15 EP disclosed