SCHEMBL196389

SCHEMBL196389

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(NC(=O)c2ccccc2)c1F

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 8/20 0.50
GAA P10253 1/20 0.48
PPARG P37231 4/20 0.47
NR1H4 Q96RI1 3/20 0.47
POLB P06746 1/20 0.46
HPGD P15428 1/20 0.46
KCNK3 O14649 1/20 0.45
KCNK9 Q9NPC2 1/20 0.45
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29292197 0.94 RXFP1 (0.47) RXFP1GAAPPARGNR1H4POLB
SCHEMBL31175832 0.93 RXFP1 (0.46) RXFP1GAAPPARGNR1H4POLB
SCHEMBL31175830 0.93 RXFP1 (0.46) RXFP1GAAPPARGNR1H4POLB
SCHEMBL21563472 0.93 RXFP1 (0.46) RXFP1GAAPPARGNR1H4POLB
SCHEMBL22212751 0.90 GAA (0.52) RXFP1GAAPPARGNR1H4POLB
SCHEMBL1766371 0.89 RXFP1 (0.50) RXFP1PPARGNR1H4KCNK3KCNK9
SCHEMBL23086317 0.88 RXFP1 (0.49) RXFP1PPARGNR1H4KCNK3KCNK9
SCHEMBL1766780 0.88 RXFP1 (0.52) RXFP1PPARGNR1H4KCNK3KCNK9
SCHEMBL1766287 0.88 RXFP1 (0.49) RXFP1PPARGNR1H4KCNK3KCNK9
SCHEMBL29409944 0.88 RXFP1 (0.54) RXFP1GAAPPARGNR1H4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580710-B2 Pesticidal active mixtures comprising aminothiazoline compounds BASF SE (DE) 2013-11-12 US claimed
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2011-09-15 US claimed
CN-101980607-A Pesticidal active mixtures comprising aminothiazoline compounds BASF SE 2011-02-23 CN claimed
EP-2325165-B1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD MITSUI CHEMICALS AGRO INC (JP) 2020-02-19 EP disclosed
EP-3102032-B1 SEED COATING FORMULATIONS AND THEIR USE FOR YIELD INCREASE BASF CORP (US) 2019-04-10 EP disclosed
EP-2346335-B1 PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2018-11-14 EP disclosed
EP-3205642-A2 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2017-08-16 EP disclosed
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase BASF CORPORATION (US) 2016-12-01 US disclosed
US-9375008-B2 Pyrazole compounds for controlling invertebrate pests BASF SE (DE) 2016-06-28 US disclosed
EP-2550264-B1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2016-06-08 EP disclosed
CN-104211688-B The pyrazole compound of controlling invertebrate pests BASF SE (DE) 2016-04-13 CN disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
CN-102088857-A Pesticidal mixtures comprising isoxazoline compounds ii BASF SE 2011-06-08 CN disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2317856-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II BASF SE (DE) 2011-05-11 EP disclosed
CN-101980607-A Pesticidal active mixtures comprising aminothiazoline compounds BASF SE 2011-02-23 CN disclosed
WO-2010040834-A2 LIQUID AQUEOUS CROP PROTECTION FORMULATIONS BASF SE (DE) 2010-04-15 WO disclosed
WO-2010003877-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II BASF SE (DE) 2010-01-14 WO disclosed
WO-2009153238-A1 AMINOTHIAZOLINE COMPOUNDS FOR COMBATING INSECTS, ARACHNIDS AND NEMATODES BASF SE (DE) 2009-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 RXFP1 1891/4885GAA 3220/4885PPARG 2115/4885
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds CBR3, AOC3, MT-CO3 RXFP1 590/4885GAA 4829/4885PPARG 3643/4885
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase CLTB, STUB1, CBLB RXFP1 4655/4885GAA 1423/4885PPARG 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.