SCHEMBL2221444

SCHEMBL2221444

BrC1=C(Br)CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6416270 1.00
SCHEMBL4923961 0.90
SCHEMBL18112474 0.86
SCHEMBL16860542 0.86 TRIM24 (0.38)
SCHEMBL31189298 0.86 TRIM24 (0.38)
SCHEMBL16860543 0.86 TRIM24 (0.38)
SCHEMBL31398609 0.78
SCHEMBL1893104 0.74
SCHEMBL1411615 0.74
SCHEMBL16860510 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111278837-B Hydrocarbon-soluble halogen and thiol/magnesium exchange reagent 雅宝德国有限责任公司 2024-04-09 CN claimed
EP-3688000-B1 HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS ALBEMARLE GERMANY GMBH (DE) 2023-11-08 EP claimed
US-11236113-B2 Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents ALBEMARLE GERMANY GMBH (DE) 2022-02-01 US claimed
EP-3688000-A1 HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS Albemarle Germany GmbH (DE) 2020-08-05 EP claimed
US-20200239496-A1 Hydrocarbon-Soluble Halogen and Thiolate/Magnesium Exchange Reagents Ludwig-Maximilians-Universitat München (DE) 2020-07-30 US claimed
CN-111278837-A Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents 雅宝德国有限责任公司 2020-06-12 CN claimed
CN-105949370-A High-strength rapid water absorption resin and preparation method thereof 青岛科技大学 2016-09-21 CN claimed
EP-4737441-A1 METHOD FOR PRODUCING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND FUJIFILM Corporation (JP) 2026-05-06 EP disclosed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-20260070931-A1 METHOD FOR MANUFACTURING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2026-03-12 US disclosed
US-20250326776-A1 ORGANOMETALLIC COMPLEX, OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2025-10-23 US disclosed
WO-2025004786-A1 METHOD FOR PRODUCING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND 富士フイルム株式会社 2025-01-02 WO disclosed
US-20240360148-A1 NITRILE SUMO INHIBITORS AND USES THEREOF CIT THERAPEUTICS LLC 2024-10-31 US disclosed
US-5576339-A Pyridyl substituted cyclopentadienes for the treatment of inflamation HUANG HORNG-CHIH (US) 1996-11-19 US disclosed
EP-0724566-A1 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-08-07 EP disclosed
WO-1995030656-A1 SUBSTITUTED CYCLOPENTADIENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-11-16 WO disclosed
US-5420287-A 1,2 diarylcyclopentenyl compounds for the treatment of inflammation G. D. SEARLE & CO. (US) 1995-05-30 US disclosed
US-5418254-A Side effect reduction G. D. SEARLE & CO. (US) 1995-05-23 US disclosed
WO-1995011883-A1 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-05-04 WO disclosed
US-5344991-A Sulfonyl or sulfamyl derivatives for treatment of arthritis and pain G.D. SEARLE & CO. (US) 1994-09-06 US disclosed